Advertisement

Degeneration of the lumbar spine and dual-energy X-ray absorptiometry measurements in patients without osteoporosis

Published:February 23, 2009DOI:https://doi.org/10.1016/j.clinimag.2008.12.005

      Abstract

      Aim

      The aim of this study was to evaluate the effects of degenerative findings on the accuracy of readings obtained by dual-energy X-ray absorptiometry (DXA) in patients without osteoporosis.

      Methods

      Twenty-four female patients who had undergone both DXA and lumbar magnetic resonance imaging were included in the study.

      Conclusion

      This study has demonstrated that degenerative radiologic changes, especially in the osteophyte area, affect bone mineral density measurements, so degeneration should be considered in the evaluation of this measurement.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Clinical Imaging
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Melton LJ
        How many women have osteoporosis now?.
        J Bone Miner Res. 1995; 10: 175-177
        • Stone KL
        • Seeley DG
        • Lui LY
        • Cauley JA
        • Ensrud K
        • Browner WS
        • Nevitt MC
        • Cummings SR
        • Osteoporotic Fractures Research Group
        BMD at multiple sites and risk of fracture of multiple types: long-term results from the Study of Osteoporotic Fractures.
        J Bone Miner Res. 2003; 18: 1947-1954
        • Ray NF
        • Chan JK
        • Thamer M
        • Melton LJ
        Medical expenditures for the treatment of osteoporotic fractures in the United States in 1995: report from the National Osteoporosis Foundation.
        J Bone Miner Res. 1997; 12: 24-35
        • Cooper C
        • Atkinson EJ
        • Jacobsen SJ
        • O'Fallon WM
        • Melton LJ
        Population-based study of survival after osteoporotic fractures.
        Am J Epidemiol. 1993; 137: 1001-1005
        • Pappou IP
        • Girardi FP
        • Sandhu HS
        • Parvataneni HK
        • Cammisa FP
        • Schneider R
        • Frelinghuysen P
        • Lane JM
        Disconcordantly high spinal bone mineral density values in patients with adult lumbar scoliosis.
        Spine. 2006; 31: 1614-1620
        • Blake GM
        • Fogelman I
        Role of dual-energy X-ray absorptiometry in the diagnosis and treatment of osteoporosis.
        J Clin Densitom. 2007; 10: 102-110
        • Kanis J
        • Glüer C
        An update on the diagnosis and assessment of osteoporosis with densitometry. Committee of Scientific Advisors, International Osteoporosis Foundation.
        Osteoporos Int. 2000; 11: 192-202
        • Lewiecki EM
        • Kendler DL
        • Kiebzak GM
        • Schmeer P
        • Prince RL
        • El-Hajj Fuleihan G
        • Hans D
        Special report on the official positions of the International Society for Clinical Densitometry.
        Osteoporos Int. 2004; 15: 779-784
        • Rand T
        • Seidl G
        • Kainberger F
        • Resch A
        • Hittmair K
        • Schneider B
        • Glüer CC
        • Imhof H
        Impact of spinal degenerative changes on the evaluation of bone mineral density with dual energy X-ray absorptiometry (DXA).
        Calcif Tissue Int. 1997; 60: 430-433
        • Genant HK
        • Wu CY
        • van Kuijk C
        • Nevitt MC
        Vertebral fracture assessment using a semiquantitative technique.
        J bone Miner Res. 1993; 8: 1137-1148
        • World Health Organisation
        Physical status: the use and interpretation of anthropometry-report of a WHO expert committee.
        World Health Organ Tech Rep Ser. 1995; 854 ([Geneva]): 312-344
        • Harada A
        • Okuizumi H
        • Miyagi N
        • Genda E
        Correlation between bone mineral density and intervertebral disc degeneration.
        Spine. 1998; 23: 857-861
        • Donescu OS
        • Battie MC
        • Videman T
        The influence of magnetic resonance imaging findings of degenerative disease on dual energy X-ray absorptiometry measurements in middle aged men.
        Acta Radiol. 2007; 48: 193-199
        • Weishaupt D
        • Zanetti M
        • Boos N
        • Hodler J
        MR Imaging and CT in osteoarthritis of the lumbar facet joints.
        Skeletal Radiol. 1999; 28: 215-219
        • Pfirrmann CW
        • Metzdorf A
        • Zanetti M
        • Hodler J
        • Boos N
        Magnetic resonance classification of lumbar intervertebral disc degeneration.
        Spine. 2001; 26: 1873-1878
        • Battie MC
        • Videman T
        • Gibbons L
        • Fisher LD
        • Manninen H
        • Gill K
        Determinants of lumbar disc degeneration. A study relating lifetime exposures and MRI findings in identical twins.
        Spine. 1995; 20: 2601-2612
        • Masud T
        • Langley S
        • Wiltshire P
        • Doyle DV
        • Spector TD
        Effect of spinal osteophytosis on bone mineral density measurements in vertebral osteoporosis.
        Br Med J. 1993; 307: 172-173
        • Margulies JY
        • Payzer A
        • Nyska M
        • Neuwirth MG
        • Floman Y
        • Robin GC
        The relationship between degenerative changes and osteoporosis in the lumbar spine.
        Clin Orthop Relat Res. 1996; 324: 145-152
        • Muraki S
        • Yammaoto S
        • Ishibashi H
        • Horiuchi T
        • Hosoi T
        • Orimo H
        • Nakamura K
        Impact of degenerative spinal diseases of the lumbar spine in elderly women.
        Osteoporos Int. 2004; 15: 724-728
        • Pye SR
        • Reid DM
        • Adams JE
        • Silman AJ
        • O'Neill TW
        Radiographic features of lumbar disc degeneration and bone mineral density in men and women.
        Ann Rheum Dis. 2006; 65: 234-238
        • Arabi A
        • Baddoura R
        • Awada H
        • Khoury N
        • Haddad S
        • Ayoub G
        • El-Hajj Fuleihan G
        Discriminative ability of dual-energy X-ray absorptiometry site selection in identifying patients with osteoporotic fractures.
        Bone. 2007; 40: 1060-1065
        • O'Gradaigh D
        • Debiram I
        • Love S
        • Richards HK
        • Compston JE
        A prospective study of disconcordance in diagnosis of osteoporosis using spine and proximal femur bone densitometry.
        Osteoporos Int. 2003; 14: 13-18
        • Reginster JY
        • Janssen C
        • Deroisy R
        • Zegels B
        • Albert A
        • Franchimont P
        Bone mineral density of the spine and the hip measured with dual energy X-ray absorptiometry: normal range and fracture threshold for western European (Belgian) postmenopausal females.
        Clin Rheumatol. 1995; 14: 68-75
        • Arlot ME
        • Sornay-Rendu E
        • Garnero P
        • Vey-Marty B
        • Delmas PD
        Apparent pre- and postmenopausal bone loss evaluated by DXA at different skeletal sites in women: the OFELY cohort.
        J Bone Miner Res. 1997; 12: 683-690