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1H MR Spectroscopy of human brain tumors: a practical approach

  • V. Callot
    Affiliations
    (Centre de Résonance Magnétique Biologique et Médicale (CRMBM), UMR 6612, CNRS-Université de la Mediterranée, 27 Blvd. Jean Moulin, F-13385 Marseilles Cedex 05, France). Eur J Radiol 2008;67:268-274.
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  • D. Galanaud
    Affiliations
    (Centre de Résonance Magnétique Biologique et Médicale (CRMBM), UMR 6612, CNRS-Université de la Mediterranée, 27 Blvd. Jean Moulin, F-13385 Marseilles Cedex 05, France). Eur J Radiol 2008;67:268-274.
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  • Y. Le Fur
    Affiliations
    (Centre de Résonance Magnétique Biologique et Médicale (CRMBM), UMR 6612, CNRS-Université de la Mediterranée, 27 Blvd. Jean Moulin, F-13385 Marseilles Cedex 05, France). Eur J Radiol 2008;67:268-274.
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  • S. Confort-Gouny
    Affiliations
    (Centre de Résonance Magnétique Biologique et Médicale (CRMBM), UMR 6612, CNRS-Université de la Mediterranée, 27 Blvd. Jean Moulin, F-13385 Marseilles Cedex 05, France). Eur J Radiol 2008;67:268-274.
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  • J.-P. Ranjeva
    Affiliations
    (Centre de Résonance Magnétique Biologique et Médicale (CRMBM), UMR 6612, CNRS-Université de la Mediterranée, 27 Blvd. Jean Moulin, F-13385 Marseilles Cedex 05, France). Eur J Radiol 2008;67:268-274.
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  • P.J. Cozzone
    Affiliations
    (Centre de Résonance Magnétique Biologique et Médicale (CRMBM), UMR 6612, CNRS-Université de la Mediterranée, 27 Blvd. Jean Moulin, F-13385 Marseilles Cedex 05, France). Eur J Radiol 2008;67:268-274.
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      Magnetic resonance spectroscopy (MRS) is proposed in addition to magnetic resonance imaging (MRI) to help in the characterization of brain tumours by detecting metabolic alterations that may be indicative of the tumour class. MRS can be routinely performed on clinical magnets, within a reasonable acquisition time and if performed under adequate conditions, MRS is reproducible and thus can be used for longitudinal follow-up of treatment. MRS can also be performed in clinical practice to guide the neurosurgeon into the most aggressive part of the lesions or to avoid unnecessary surgery, which may furthermore decrease the risk of surgical morbidity.
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