Celiac disease is a malabsorption syndrome in which dietary gluten damages the small
bowel mucosa. Gluten contains gliadin, the primary toxic component that is primarily
found in wheat, barley, and rye products. The initial diagnosis of coeliac disease
is usually made by endoscopic biopsy of the jejunum, although sometimes imaging features
can suggest the diagnosis. Once a diagnosis is made, patients need to be diet compliant
and monitored for potential complications. Many complications are more common when
dietary compliance is poor. Complications include intussusception (usually intermittent),
ulcerative jejunitis, osteomalacia, cavitating lymph node syndrome, and an increased
risk of malignancies such as lymphoma, adenocarcinoma, and squamous cell carcinoma.
Radiological evaluation is central in the evaluation of these complications. Imaging
may assist in both the diagnosis and staging of complications as well as in enabling
radiologically guided percutaneous biopsy for complications of coeliac disease such
as lymphoma. As celiac disease is a relatively common disorder; it is likely that
most radiologists will encounter the disease and its potential complications. The
aim of this review article was to discuss and illustrate the role of modern radiology
in evaluating the many presentations of this complex disease.
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Clinical ImagingAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
Article info
Identification
Copyright
© 2008 Published by Elsevier Inc.
