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F-18 FDG PET in detecting uterine leiomyoma

  • Chun-Yi Lin
    Affiliations
    Department of Nuclear Medicine, Show Chwan Memorial Hospital, Changhua, Taiwan
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  • Hueisch-Jy Ding
    Affiliations
    Department of Radiological Technology, I-Shou University, Kaohsiung, Taiwan
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  • Yen-Kung Chen
    Affiliations
    Department of Nuclear Medicine and PET Center, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan
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  • Chiu-Shoung Liu
    Correspondence
    Corresponding authors. C.-S. Liu is to be contacted at Department of Community Medicine and Health Examination Center, China Medical University Hospital, No. 2, Yuh-Der Road, Taichung 404, Taiwan. C.-H. Kao, Department of Nuclear Medicine and PET Center, China Medical University Hospital, No. 2, Yuh-Der Road, Taichung 404, Taiwan. Tel.: +886 4 22052121x3475; fax: +886 4 22070675.
    Affiliations
    Department of Community Medicine and Health Examination Center, China Medical University Hospital, Taichung, Taiwan
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  • Cheng-Chieh Lin
    Affiliations
    Department of Family Medicine, China Medical University Hospital, Taichung, Taiwan
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  • Chia-Hung Kao
    Correspondence
    Corresponding authors. C.-S. Liu is to be contacted at Department of Community Medicine and Health Examination Center, China Medical University Hospital, No. 2, Yuh-Der Road, Taichung 404, Taiwan. C.-H. Kao, Department of Nuclear Medicine and PET Center, China Medical University Hospital, No. 2, Yuh-Der Road, Taichung 404, Taiwan. Tel.: +886 4 22052121x3475; fax: +886 4 22070675.
    Affiliations
    Department of Nuclear Medicine and PET Center, China Medical University Hospital, Taichung 404, Taiwan
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Published:September 21, 2007DOI:https://doi.org/10.1016/j.clinimag.2007.07.006

      Abstract

      Purpose

      Uterine leiomyoma, benign tumors of the human uterus, are clinically apparent in about 25% of women and the most common solid pelvic tumors. The purpose of this study was to investigate the F-18 2-fluoro-2-deoxy-D-glucose (FDG) uptake in the uterine leiomyoma and assess the correlation between the intensity of FDG uptake in the uterine leiomyomas and menstrual cycle.

      Methods

      A total of 589 charts of healthy females examined by whole body FDG positron emission tomography (PET) for health screening examination were reviewed retrospectively. Twenty-two of them were suspected gynacecological tumors and referred to the department of gynacecology to ascertain the nature of the causes. Final diagnosis as uterine leiomyomas were made based on uterine sonography, pelvic computed tomography, or pelvic magnetic resonance imaging scans. We defined FDG uptake as Grade I when FDG uptake was less than liver uptake, Grade II when FDG uptake was equal to liver uptake, and Grade III when FDG uptake was greater than liver uptake. The menstrual cycle was recorded on the day of performing FDG PET in premenopausal women.

      Results

      The FDG uptake in the uterine region is Grade I in three of these 22 females (13.65%), Grade II in 16 (72.7%), and Grade III in 3 (13.65%).

      Conclusion

      There is no significant correlation between the intensity of FDG uptake in the uterine leiomyomas and menstrual cycle (P=.914).

      Keywords

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