Abstract
Purpose
Uterine leiomyoma, benign tumors of the human uterus, are clinically apparent in about
25% of women and the most common solid pelvic tumors. The purpose of this study was
to investigate the F-18 2-fluoro-2-deoxy-D-glucose (FDG) uptake in the uterine leiomyoma
and assess the correlation between the intensity of FDG uptake in the uterine leiomyomas
and menstrual cycle.
Methods
A total of 589 charts of healthy females examined by whole body FDG positron emission
tomography (PET) for health screening examination were reviewed retrospectively. Twenty-two
of them were suspected gynacecological tumors and referred to the department of gynacecology
to ascertain the nature of the causes. Final diagnosis as uterine leiomyomas were
made based on uterine sonography, pelvic computed tomography, or pelvic magnetic resonance
imaging scans. We defined FDG uptake as Grade I when FDG uptake was less than liver
uptake, Grade II when FDG uptake was equal to liver uptake, and Grade III when FDG
uptake was greater than liver uptake. The menstrual cycle was recorded on the day
of performing FDG PET in premenopausal women.
Results
The FDG uptake in the uterine region is Grade I in three of these 22 females (13.65%),
Grade II in 16 (72.7%), and Grade III in 3 (13.65%).
Conclusion
There is no significant correlation between the intensity of FDG uptake in the uterine
leiomyomas and menstrual cycle (P=.914).
Keywords
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Article info
Publication history
Published online: September 21, 2007
Accepted:
July 11,
2007
Received:
June 10,
2007
Identification
Copyright
© 2008 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
