Hypothesis: Early stage non-small cell lung cancer (NSCLC) is a major public health problem.
The tumors are aggressive and the patients are typically frail secondary to smoking-related
health issues and advanced age. Radical surgery is an effective standard therapy.
However, a significant number of patients are not surgical candidates and the postoperative
morbidity is significant. Traditional irradiation has been utilized with limited success
due to poor local tumor control and significant pulmonary toxicity. Radioablation
has been evaluated recently, with promising results. However, broader acceptance has
been slowed by its variable, tedious application. The CyberKnife system has been successfully
utilized to treat stationary tumors anywhere in the body. With the Synchrony™ Motion
Tracking Module, lung tumors that are influenced by the motion of respiration may
be treated accurately and effectively with minimal patient discomfort. The system
accomplishes this by utilizing a continually updated model predicting target location.
This model is generated by the use of continuously sampled surface visible red light
emitting tracking markers, as sampled by a camera array and episodically sampled target
fiducials as measured by the CyberKnife X-ray targeting system.
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Publication history
Published online: May 26, 2005
Identification
Copyright
© 2005 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
