The aim of this study was to determine whether preoperative MR mammography could predict
the extent of breast cancer in patients with dense breasts or whether dense parenchyma
will lead to false-positive or inconclusive examinations. Sixty-seven patients with
dense breasts with a malignant breast tumor planned for conservative surgery were
reviewed. Detection rates of mammography, ultrasound, and MR mammography were studied,
and the diameters of the lesions were measured and compared with pathological examination.
Pathology revealed breast cancer in 65 patients. Sensitivity for detection of index
lesions was 83% for mammography, 70.8% for ultrasound, and 98% for MR mammography.
Mammography underestimated tumor extent in 37%, ultrasound in 40%, and MR in 12.5%.
Of the 20 patients (31%) with multifocal or multicentric carcinoma, mammography detected
the lesions in 35%, ultrasound in 30%, and MR in 100%, with a false-positive rate
of 12.5%, 14%, and 23%. The MR mammography is more accurate in assessing tumor extent
and multifocality in patients with dense breasts, but benign changes may lead to false-positive
examinations.
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Publication history
Published online: October 05, 2004
Identification
Copyright
© 2004 Published by Elsevier Inc.
