This study aims to confirm the relationship between gestational age (GA) and transverse
cerebellar diameter (TCD), to define the prediction of GA by TCD, and to assess the
reliability of TCD measurements. Infants were included in the study if they had a
routine cranial ultrasound scan by day 3, and the TCD was measured. Infants were excluded
from the study if the GA was not known, if there was any cranio-spinal malformation
or grade 3 or 4 intraventricular haemorrhage (IVH). The GA assessment was an early
pregnancy scan or certain dates. Cranial ultrasound scans were done with a LOGIQ 500
scanner (GE Medical Systems, Waukesha, WI, USA) with a 7-MHz curvilinear sector probe
(GE LOGIQ-C721; GE Medical Systems). The posterior fossa was scanned using the asterion
as the acoustic window with the TCD measured in the coronal plane. Intra- and interobserver
reliability was assessed. A total of 221 infants of known GA had their TCD measured.
The linear regression for GA versus TCD is: GAweeks=(0.470×TCDmillimetres)+13.162 (r=.89, r2=.79, P<.001). The 95% confidence interval predicts GA to ±2.33 weeks for given TCD. Intra-
and interobserver intraclass correlation coefficients are .98 and .99, respectively.
Transverse cerebellar diameter correlates closely with GA and predicts GA to ±2.33
weeks. Measurements of TCD have excellent reproducibility.
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© 2002 Elsevier Science Inc. Published by Elsevier Inc. All rights reserved.
