Abstract
Objective: Improvement of neurosurgical techniques with a more detailed description of brain
tumors and their functional environment. Methods: We performed: (1) anatomical magnetic resonance imaging (MRI) for reference, (2)
functional sequences dedicated to the adjacent cortical structures (sensorimotor,
visual, language paradigms), and (3) thallium 201 cerebral tomoscintigraphy to visualize
active tumor invasion. Data were transferred to a workstation for automatic registration.
Results: All data were combined into one synthetic image showing the foci of high proliferative
activity, which have to be completely resected, and the peritumoral functional structures,
which have to be spared in order to minimize postoperative sequelae. This trimodal
image is entered into a surgical neuronavigation computer for preoperative planning
in order to outline tumoral target and functional risk areas. All this information
is displayed in the operative microscope (Zeiss MKM) optically linked to MR images.
This multimodality technique diminishes operative time by reducing electrocorticography
and improves the operative short-term outcome. Conclusion: Multimodal imaging is useful for optimization of neurosurgical tumor resection.
Keywords
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Article info
Publication history
Received:
May 25,
2001
Identification
Copyright
© 2002 Elsevier Science Inc. Published by Elsevier Inc. All rights reserved.
