MRI features of spinal ganglioglioma

      This paper is only available as a PDF. To read, Please Download here.


      Spinal cord ganglioglioma is a rare tumor most often encountered in the first three decades. Scanty computed tomography (CT) reports on the tumor describe it as a hypodense or cerebrospinal fluid (CSF) dense area with little contrast enhancement despite its solid nature. We report two cases of spinal ganglioglioma both involving almost the whole spinal cord. On magnetic resonance imaging (MRI), the tumors appear hypointense to the spinal cord on T1 and hyperintense to the cord on T2 images, and were mainly solid at exploration. It is important to recognize these tumors as long survival can be achieved after surgical resection.


      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to Clinical Imaging
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • Henry J.M.
        • Heffner R.R.
        • Easle K.M.
        Ganglioglioma of CNS: A clinicopathological study of 50 cases.
        J Neuropathol Exp Neurol. 1978; 37: 626
      1. Russell D.S. Rubinstein L.J. Pathology of Tumors of the Nervous System. Williams & Wilkins, Baltimore1989
        • Bell W.O.
        • Packer R.J.
        • Seigel K.R.
        • et al.
        Leptomeningeal spread of intramedullary spinal cord tumors. Report of three cases.
        J Neurosurg. 1988; 69: 295-300
        • Russel D.S.
        • Rubinstein L.J.
        Ganglioglioma: a case with long history and malignant evolution.
        J Neuropathol Exp Neurol. 1962; 21: 183-185
        • Kitano M.
        • Takayama S.
        • Nagao T.
        • Yoshimura O.
        Malignant ganglioglioma of the spinal cord.
        Acta Pathol Jpn. 1987; 37: 1009-1018
        • Zimmerman H.
        Introduction to tumors of the central nervous system.
        in: 2nd ed. Pathology of the Nervous System. Vol. 2. McGraw-Hill, New York1971: 1947-1951
        • Lichtenstein B.W.
        • Zeitlin H.
        Ganglioglioneuroma of the spinal cord associated with psuedosyringomyelia. A histologic study.
        Arch Neurol Psychiatry. 1937; 37: 1356-1370
        • Wald U.
        • Levy P.J.
        • Rappaport Z.H.
        • Michowitz S.D.
        • Schuger L.
        • Shalit M.N.
        Conus ganglioglioma in a 2 1/2-year-old boy. Case Report.
        J Neurosurg. 1985; 62: 142-144
        • Albright L.
        • Byrd R.P.
        Ganglioglioma of the entire spinal cord.
        Childs Brain. 1980; 6: 274-280
        • Bevilacqua G.
        • Sarnelli R.
        Ganglioglioma of the spinal cord, a case with long survival.
        Acta Neuropathol. 1959; 48: 239-242
        • Johannsson J.H.
        • Rekate H.L.
        • Roessmann U.
        Gangliogliomas: pathological and clinical correlation.
        J Neurosurg. 1981; 54: 58-63
        • Citron N.
        • Edgar M.A.
        • Sheehy J.
        • Thomas D.G.T.
        Intramedullary spinal cord tumours presenting as scoliosis.
        J. Bone Joint Surg. 1984; 66-B: 513-517
        • Katz M.C.
        • Kier E.L.
        • Schechter M.M.
        The radiology of gangliogliomas and ganglioneuromas of the central nervous system.
        Neuroradiology. 1972; 4: 69-73
        • Kalyan-Raman U.P.
        • Olivero W.C.
        Ganglioglioma: a correlative clinicopathological and radiological study of ten surgically treated cases with follow-up.
        Neurosurgery. 1987; 20: 428-433
        • Sutton L.N.
        • Packer R.J.
        • Rorke L.B.
        • et al.
        Cerebral gangliogliomas during childhood.
        Neurosurgery. 1983; 13: 124-128
        • Pojunas K.
        • Williams A.L.
        • Daniels D.L.
        • Haughton V.M.
        Syringomyelia and hydromyelia: magnetic resonance evaluation.
        Radiology. 1984; 153: 679-683
        • Sze G.
        Gadolinium-DTPA in spinal disease.
        Radiol Clin North Am. 1988; 26: 1009-1024
        • Nelson K.L.
        • Modic M.T.
        in: Runge V.M. Enhanced magnetic resonance imaging. CV Mosby, St. Louis1989: 193-210
        • Garrido E.
        • Becker L.F.
        • Hoffman H.J.
        • Hendrick E.B.
        • Humphreys R.
        Gangliogiomas in children-a clinicopathologic study.
        Childs Brain. 1978; 4: 339-346