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Focal cortical dysplasia on magnetic resonance imaging: A case report

  • Martha A. Nowell
    Affiliations
    Department of Radiology, the Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA

    Department of Neurology, the Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
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  • Robert I. Grossman
    Correspondence
    Address reprint requests to: Robert I. Grossman, MD, Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, Pennsylvania 19104.
    Affiliations
    Department of Radiology, the Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA

    Department of Neurology, the Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
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  • Roger Packer
    Affiliations
    Department of Radiology, the Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA

    Department of Neurology, the Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
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  • David B. Hackney
    Affiliations
    Department of Radiology, the Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA

    Department of Neurology, the Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
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  • Herbert I. Goldberg
    Affiliations
    Department of Radiology, the Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA

    Department of Neurology, the Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
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  • Larissa T. Bilaniuk
    Affiliations
    Department of Radiology, the Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA

    Department of Neurology, the Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
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  • Robert A. Zimmerman
    Affiliations
    Department of Radiology, the Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA

    Department of Neurology, the Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
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      Abstract

      A case report of an 11 year old boy with new onset of a seizure disorder is presented. A computed tomography scan demonstrated a noncalcified, nonenhancing focal region of abnormal cortex. A magnetic resonance imaging scan delineated both an isointense area of abnormally thickened gyri and linear areas of abnormal high signal intensity in the subjacent white matter. A review of the radiologic and pathologic literature suggests that this lesion represents the entity focal cortical dysplasia as described by Taylor, et al. This abnormality is part of a spectrum of disorders including hamartomas (of tuberous sclerosis), focal cortical dysplasia and heterotopias.

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