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Research Article| Volume 12, ISSUE 1, P19-24, January 1988

The role of computed tomography in evaluation of skeletal metastases

DOI:https://doi.org/10.1016/0149-936X(88)90023-9
The role of computed tomography in evaluation of skeletal metastases
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      Abstract

      Computed tomography was performed in 100 patients for additional evaluation of suspected skeletal metastases following radionuclide bone scanning in 86 patients and conventional radiography in all. A retrospective review of these cases revealed that the majority (78%) involved the spine and pelvis. Computed tomography contributed to the diagnosis of a malignancy by revealing a definite destructive lesion of bone in 27 patients who had an abnormal radionuclide bone scan, a normal or inconclusive radiograph, or both. It excluded a malignant lesion in 19 patients. In 38 patients, computed tomography provided additional information that contributed to such aspects of patient care as obtaining tissue diagnosis, determining the extent of lesions, and evaluating the response to treatment. False diagnoses were made in two patients.
      Detection by computed tomography of a skeletal lesion and histologic documentation, frequently by computed tomography-guided percutaneous needle aspiration biopsy, greatly curtailed an otherwise extensive search for the primary site. Furthermore, this information altered the treatment plan by obviating the need for radical resection or biopsy of the primary tumor and by directing the choice of an appropriate chemotherapeutic regimen.

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      References

        • Mall J.C.
        • Beckerman C.
        • Hoffer P.B.
        • Gottschalk H.
        A unified radiological approach to the detection of skeletal metastases.
        Radiology. 1976; 118: 323-328
        • Pagami J.J.
        • Libshitz H.I.
        Imaging bone metastases.
        Rad Clin North Am. 1982; 20: 545-560
        • Corcoran R.J.
        • Thrall J.H.
        • Kyle R.W.
        • Kaminski R.J.
        • John M.C.
        Solitary abnormalities in bone scans of patients with extraosseous malignancies.
        Radiology. 1976; 121: 663-667
        • Levine E.
        • Lee K.R.
        • Neff J.R.
        • et al.
        Comparison of computed tomography and other imaging modalities in the evaluation of musculoskeletal tumors.
        Radiology. 1979; 131: 431-437
        • Kido D.K.
        • Gould R.
        • Taati F.
        • Duncan A.
        • Schnur J.
        Comparative sensitivity of CT scans, radiographs, and radionuclide bone scans in detecting metastaic calvarial lesions.
        Radiology. 1978; 128: 371-375
        • Cacayorin E.D.
        • Kieffer S.A.
        Application and limitations of computed tomography of the spine.
        Rad Clin North Am. 1982; 20: 185-206
        • Green B.A.
        • Diaz R.D.
        • Post M.J.D.
        The diagnosis of spinal column and spinal cord tumors and emphasis on the value of computed tomography.
        in: Post M.J.D. Computed tomography of the spine. Williams & Wilkins, Baltimore1984: 659-695
        • Muindi J.
        • Coombes R.C.
        • Golding S.
        • et al.
        The role of computed tomography in the detection of bone metastases in breast cancer patients.
        Br J Radiol. 1983; 56: 233-236
        • Kori S.H.
        Computed tomographic evaluation of bone and soft tissue metastases.
        in: Weiss L. Gilbert H. Bone metastasis. Hall, Boston1981: 245-257
        • Rafii M.
        • Firooznia H.
        • Golimbu C.
        • Beranbaum E.
        CT of skeletal metastasis.
        Semin Ultrasound CT MR. 1986; 7: 371-379
        • Galasko C.B.S.
        The anatomy and pathways of skeletal metastases.
        in: Weiss L. Gilbert H. Bone metastasis. Hall, Boston1981: 49-63
        • Helms C.A.
        • Cann E.C.
        • Brunelle F.O.
        • et al.
        Detection of bonemarrow metastases using quantitative computed tomography.
        Radiology. 1981; 140: 745-750
        • DiSteffano A.
        • Tashima C.K.
        • Yong Yap H.
        • Hortobagyi G.N.
        Bone marrow metastases without cortical bone involvement in breast cancer patients.
        Cancer. 1979; 44: 196-198
        • Hardy D.C.
        • Murphy W.A.
        • Gilula L.
        Computed tomography in planning percutaneous bone biopsy.
        Radiology. 1980; 134: 447-450

      Article info

      Identification

      DOI: https://doi.org/10.1016/0149-936X(88)90023-9

      Copyright

      © 1988 Published by Elsevier Inc.

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