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Merkel cell carcinoma

  • Susan Marks
    Affiliations
    Departments of Radiology and Surgical Pathology, University of Southern California School of Medicine, Los Angeles, California, U.S.A.
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  • D. Randall Radin
    Correspondence
    Address reprint requests to: D. Randall Radin, MD, Department of Radiology, Los Angeles County-USC Medical Center, 1200 North State Street, Los Angeles, California 90033.
    Affiliations
    Departments of Radiology and Surgical Pathology, University of Southern California School of Medicine, Los Angeles, California, U.S.A.
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  • Parakrama Chandrasoma
    Affiliations
    Departments of Radiology and Surgical Pathology, University of Southern California School of Medicine, Los Angeles, California, U.S.A.
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      This paper is only available as a PDF. To read, Please Download here.

      Abstract

      Merkel cell carcinoma is a rare malignant neoplasm of the skin which is locally invasive and frequently metastasizes to lymph nodes, liver, lungs, bone, and brain. Computed tomographic and pathologic findings in an elderly woman with Merkel cell carcinoma of the buttock and regional nodal metastasis are reported. The presence of calcitonin and neuron-specific enolase within the tumor supports the theory that Merkel cell carcinoma is a neuroendocrine tumor derived from the APUD (amine precursor uptake and decarboxylase) system.

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