Advertisement

Computed tomography in experimental allergic encephalomyelitis—Preliminary results

      This paper is only available as a PDF. To read, Please Download here.

      Abstract

      Four dogs were immunized with a mixture of spinal cord homogenate and complete Freund's adjuvant. One of these dogs developed hyperacute allergic encephalomyelitis. Cranial computed tomography in this animal demonstrated a low absorption area in the internal capsule that corresponded to the pathologic lesion. Computed tomography scanning may be a useful tool in monitoring experimental allergic encephalomyelitis.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Clinical Imaging
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Johnson K.P.
        Multiple sclerosis and the immune system.
        Arch Neurol. 1980; 37: 535-536
        • Paterson P.Y.
        Experimental allergic encephalomyelitis and autoimmune disease.
        Adv Immunol. 1966; 5: 131-208
        • Eylar E.
        • Westall F.
        • Brostoff S.
        Allergic encephalomyelitis and encephalitogenic peptide derived from the basic protein of myelin.
        J Biol Chem. 1971; 246: 3418-3424
        • Lisak R.P.
        Multiple sclerosis: evidence for immunopathogeneses.
        Neurology. 1980; 30: 99-105
        • Weinstein M.A.
        • Lederman R.J.
        • Rothner A.D.
        • et al.
        Interval computed tomography in multiple sclerosis.
        Radiology. 1978; 129: 689-694
        • Haughton V.M.
        • Ho K.C.
        • Williams A.L.
        • Eldevik O.P.
        CT detection of demyelinated plaques in multiple sclerosis.
        Am J Roentgenol. 1979; 132: 213-215
        • Knight S.C.
        Cellular immunity in multiple sclerosis.
        Br Med Bull. 1977; 33: 45-50
        • Smith M.E.
        Proteinase inhibitors and the suppression of EAE.
        in: Davison A.N. Cuzner M.L. The suppression of experimental allergic encephalomyelitis and multiple sclerosis. Academic, New York1980: 211-226
        • Paterson P.Y.
        Autoimmune neurological disease: experimental animal systems and implications for multiple sclerosis.
        in: Talal N. Autoimmunity: genetic, immunologic, virologic, and clinical aspects. Academic, New York1977: 643-692