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Abstract
Two cases of adult pulmonary alveolar proteinosis are presented with emphasis on the
computed tomographic findings in both cases. Each patient demonstrated a pattern of
diffusely increased lung density on both standard radiographic and computed tomographic
examinations of the lung. There was no evidence of adenopathy, pleural effusion, or
cardiomegaly in either patient. The diagnosis of pulmonary alveolar proteinosis was
established in both patients by open lung biopsy. The optical microscopy and electron
microscopy examinations of the biopsy material in each instance demonstrated marked
filling of the alveoli with periodic-acid-Schiff-positive material and intraalveolar
lamellar bodies. The diagnosis of sarcoid was entertained prior to the open lung biopsy
in one patient, a young adult black male. Although the computed tomographic appearance
was similar in each case and of no value in the diagnosis of pulmonary alveolar proteinosis,
it was helpful in assessing the extent of the disease within the lung.
Keywords
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Footnotes
☆The views expressed herein are those of the authors and do not necessarily reflect the views of the US Army or the Department of Defense.
Identification
Copyright
© 1984 Published by Elsevier Inc.