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Lissencephaly: Computed tomographic diagnosis

  • J.Powell Williams
    Correspondence
    Address reprint requests to: J. Powell Williams, MD, Department of Radiology, University of South Alabama College of Medicine, 2451 Fillingim Street, Mobile, Alabama 36617.
    Affiliations
    Department of Radiology, University of South Alabama College of Medicine, 2451 Fillingim Street, Mobile, Alabama, USA
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  • John N. Joslyn
    Affiliations
    Department of Radiology, University of South Alabama College of Medicine, 2451 Fillingim Street, Mobile, Alabama, USA
    Search for articles by this author
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      Abstract

      Lissencephaly is a rare congenital condition with distinctive brain changes. Most of these changes were demonstrated on computed tomography, and include lack of cortical sulci and gyri; calcification in the region of paraphysis; wide, shallow sylvian fissures; colpocephaly; poor development of white matter; and persistent cavum septum pellucidum and cavum vergae.

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