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Bone-forming gastric metastases in muscle—Computed tomographic demonstration

  • David L. Obley
    Correspondence
    Address reprint requests to: David L. Obley, M.D., Department of Radiology, Presbyterian-University Hospital, DeSoto and O'Hara Streets, Pittsburgh, PA 15212.
    Affiliations
    Departments of Radiology, Pathology, Rheumatology and Clinical Immunology, and Medicine, Presbyterian-University Hospital, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
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  • B.Simon Slasky
    Affiliations
    Departments of Radiology, Pathology, Rheumatology and Clinical Immunology, and Medicine, Presbyterian-University Hospital, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
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  • Robert L. Peel
    Affiliations
    Departments of Radiology, Pathology, Rheumatology and Clinical Immunology, and Medicine, Presbyterian-University Hospital, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
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  • Lewis H. Rosenbaum
    Affiliations
    Departments of Radiology, Pathology, Rheumatology and Clinical Immunology, and Medicine, Presbyterian-University Hospital, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
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  • John J. Nicholas
    Affiliations
    Departments of Radiology, Pathology, Rheumatology and Clinical Immunology, and Medicine, Presbyterian-University Hospital, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
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  • Lawrence D. Ellis
    Affiliations
    Departments of Radiology, Pathology, Rheumatology and Clinical Immunology, and Medicine, Presbyterian-University Hospital, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
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      Abstract

      Bone-forming metastases to soft tissues and muscle are a rare entity. An unusual case of heterotopic ossification occurring within metastases to muscle arising from a primary gastric adenocarcinoma is reported. No bone was found in the primary gastric malignancy. There is one prior report of ossification in muscle occurring in metastases from gastric malignancy, but no previous computed tomographic demonstration of this. The mechanism of osseous metaplasia is discussed, but its precise morphogenesis remains obscure.

      Keywords

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