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Abstract
A review is given f the known response of animal tissues in terms of the NMR parameters
T1 (the spin-lattice relaxation time), T2 (the spin-spin relaxation time), and D (the molecular diffusion coefficient). Correlation
is made between the behavior of these parameters and water cncentration variations
in tissues, with particular reference to concentration changesin cancerous tissue.
The correlation is discussed in terms of the various physical models ofr intracellular
water. Finally, the significance of these results to the optimization of the NMR radiological
technique is examined.
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© 1981 Published by Elsevier Inc.