Clinical Imaging RSS feed: Current Issue. Clinical Imaging provides comprehensive coverage of new technology, new applications, and important issues concerning all diagnostic imaging methods. Under the editorship of Joseph P. Whalen, M.D., Clinical Imaging explores the relative merits of established and developing diagnostic imaging technology, with regard to cost effectiveness, safety, and propriety where specific disorders and physiological systems are concerned. The journal publishes: • Original articles – peer-reviewed reports of new clinical developments • "Radiology Pathology Conference" features – a brief clinical history with physical findings, followed by a discussion of the radiologic imagings with a detailed correlation of the pathological findings • Review articles – an overview of a key topic, with an invited editorial on the same subject • Case reports – limited to important new observations • Abstracts – summaries of significant papers in related journals • Book Reviews From ultrasound to MRI, Clinical Imaging provides essential information for radiologists, radiology residents, and radiologic technologists. http://www.clinicalimaging.org/?rss=yesElsevier Inc.en © 2012 Published by Elsevier Inc. All rights reserved. Clinical Imaging0899-7071363May 2012 © 2012 Published by Elsevier Inc. All rights reserved. healthpermissions@elsevier.comhttp://www.clinicalimaging.org/article/PIIS0899707112001416/abstract?rss=yesContents10.1016/S0899-7071(12)00141-6Clinical Imaging 36, 3 (2012)2012-05-01Clinical Imaging2012-05-01363S0899-7071(11)X0009-8iiihttp://www.clinicalimaging.org/article/PIIS0899707111001720/abstract?rss=yesAbstract: Objective: To systematically review the role of 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) in evaluating treatment response to imatinib or other drugs in gastrointestinal stromal tumors (GIST).Methods: A comprehensive literature search of published studies through February 2011 in PubMed/MEDLINE and EMBASE databases was performed.Results: We identified 19 studies including 628 patients with GIST. Main findings of included studies are presented.Conclusions: 18F-FDG PET has a significant value in assessing treatment response to imatinib or other drugs in GIST patients. 18F-FDG PET allows an early assessment of treatment response and is a strong predictor of clinical outcome.18F-Fluorodeoxyglucose positron emission tomography in evaluating treatment response to imatinib or other drugs in gastrointestinal stromal tumors: a systematic reviewGiorgio Treglia, Paoletta Mirk, Antonella Stefanelli, Vittoria Rufini, Alessandro Giordano, Lorenzo Bonomo10.1016/j.clinimag.2011.08.012Clinical Imaging 36, 3 (2012)2011-09-26Clinical Imaging2011-09-26363S0899-7071(11)X0009-8Review Article167175http://www.clinicalimaging.org/article/PIIS0899707111001847/abstract?rss=yesAbstract: The aim was to investigate changes in the tumor bed on magnetic resonance mammography (MRM) after intraoperative radiotherapy (IORT) and whether they would limit the diagnostic value of posttherapeutic MRM. We retrospectively investigated 36 patients undergoing MRM after IORT (median interval 2.8 years, range 0.4–7.1). Wound cavities with fat necrosis were common after IORT (81%). They were associated with persisting contrast enhancement, i.e., enhancement was mostly seen irrespective of the posttherapeutic interval. It normally presented as rim enhancement and did not cause any diagnostic uncertainty if viewed together with other tissue characteristics. We do not expect a limited diagnostic value of MRM after IORT.First description of MR mammographic findings in the tumor bed after intraoperative radiotherapy (IORT) of breast cancerKlaus Wasser, Andreas Schnitzer, Dorothee Engel, Julia Krammer, Frederik Wenz, Uta Kraus-Tiefenbacher, Marc Suetterlin, Stefan O. Schoenberg, Gerald Weisser10.1016/j.clinimag.2011.08.024Clinical Imaging 36, 3 (2012)2011-11-02Clinical Imaging2011-11-02363S0899-7071(11)X0009-8Original Articles176184http://www.clinicalimaging.org/article/PIIS0899707111001811/abstract?rss=yesAbstract: We aimed to investigate the impact of chronic obstructive pulmonary disease (COPD) exacerbation on cerebral blood flow (CBF). In 21 COPD patients — in both exacerbation and stable phases —Doppler ultrasonographies of internal carotid artery (ICA) and vertebral artery (VA) were performed. There were significant differences in total, anterior and posterior CBF, ICA and VA flow volumes in exacerbated COPD compared to stable COPD. Total CBF was correlated with cross-sectional areas of left and right ICA, whereas independent predictor of total CBF was cross-sectional area of right ICA. Increased CBF might indicate cerebral autoregulation-mediated vasodilatation to overcome COPD exacerbation induced hypoxia.Impact of COPD exacerbation on cerebral blood flowSema Yildiz, Ihsan Kaya, Hasan Cece, Mehmet Gencer, Zeki Ziylan, Funda Yalcin, Ozlem Turksoy10.1016/j.clinimag.2011.08.021Clinical Imaging 36, 3 (2012)2011-11-02Clinical Imaging2011-11-02363S0899-7071(11)X0009-8Original Articles185190http://www.clinicalimaging.org/article/PIIS0899707111001975/abstract?rss=yesAbstract: The objective of this study was to evaluate the clinical application of hemostatic percutaneous therapy of liver and spleen trauma under contrast-enhanced ultrasound (CEUS) guidance. A total of 83 patients with 88 traumatic organ lesions were included in this study. Liver or spleen lesions were treated by percutaneous injection of haemocoagulase atrox and α-cyanoacrylate under CEUS guidance. The results showed that one treatment was sufficient to successfully control hemorrhaging in 86 of 88 traumatic organ lesions. In 2 of 88 traumas, a second percutaneous hemostatic treatment was necessary. Percutaneous treatment of blunt hemorrhagic trauma under CEUS guidance is a feasible and safe adjunct to observation in the nonoperative management.Percutaneous treatment of blunt hepatic and splenic trauma under contrast-enhanced ultrasound guidanceFaqin Lv, Jie Tang, Yukun Luo, Yongkang Nie, Ziyu Jiao, Tanshi Li, Xuan Zhou10.1016/j.clinimag.2011.09.013Clinical Imaging 36, 3 (2012)2011-11-07Clinical Imaging2011-11-07363S0899-7071(11)X0009-8Original Articles191198http://www.clinicalimaging.org/article/PIIS0899707111001768/abstract?rss=yesAbstract: Purpose: To explore the findings of diffusion-weighted imaging (DWI) and the diffusion characteristics on patellar cartilage in healthy adults.Materials and methods: Thirty healthy subjects were studied on SIEMENS 3.0-T Trio Tim magnetic resonance (MR) scanner. The apparent diffusion coefficient (ADC) values of the patellar cartilage were measured in different areas.Results: The patellar cartilage demonstrated homogeneously high signal intensity on the images of DWI and maps of ADC. The ADC values displayed a spatial dependency, approximately (1.17±0.31)×10−3 mm2/s of the entire cartilage.Conclusions: Diffusion-weighted MR imaging may display articular cartilage structure. There is a consistent pattern of spatial variation of the ADC values.Human patellar cartilage: echo planar diffusion-weighted MR imaging findings at 3.0 TShao-Cheng Zhu, Da-Peng Shi, Ang Xuan10.1016/j.clinimag.2011.08.016Clinical Imaging 36, 3 (2012)2011-10-13Clinical Imaging2011-10-13363S0899-7071(11)X0009-8Original Articles199202http://www.clinicalimaging.org/article/PIIS0899707111001732/abstract?rss=yesAbstract: Objective: The objective was to compare the diagnostic accuracy of conventional radiography and ultrasonography (US) for the diagnosis of suspected bone fractures.Method: Eighty-six patients were assessed using conventional radiography and US on the affected bone district.Results: Radiographic and sonographic findings were concordant in 93% of cases. In one case, US suggested a fracture not seen on radiographic assessment. Ultrasonography showed a sensitivity of 0.94 and a specificity of 0.92.Conclusion: In clinical practice, US could become the first diagnostic approach.Sonographic evaluation of bone fractures: a reliable alternative in clinical practice?Valeria Beltrame, Roberto Stramare, Nicola Rebellato, Federico Angelini, Anna Chiara Frigo, Leopoldo Rubaltelli10.1016/j.clinimag.2011.08.013Clinical Imaging 36, 3 (2012)2011-09-30Clinical Imaging2011-09-30363S0899-7071(11)X0009-8Original Articles203208http://www.clinicalimaging.org/article/PIIS0899707111001756/abstract?rss=yesAbstract: Malignant peripheral nerve sheath tumor (MPNST) is a relatively rare soft tissue malignant tumor. Most of reports currently are pathological articles and clinical case reports and most of them are MPNST in the thorax, abdomen or extremities. Imaging report of spinal MPNST is very rare, and MPNST is easy to be misdiagnosed. In this study, we explored the computed tomography and magnetic resonance imaging manifestations of MPNST that occurred in the spine and to improve the preoperative diagnostic accuracy of MPNST.Malignant peripheral nerve sheath tumor in spine: imaging manifestationsNing Lang, Xiao-Guang Liu, Hui-Shu Yuan10.1016/j.clinimag.2011.08.015Clinical Imaging 36, 3 (2012)2011-10-13Clinical Imaging2011-10-13363S0899-7071(11)X0009-8Original Articles209215http://www.clinicalimaging.org/article/PIIS0899707111002348/abstract?rss=yesThe objective was to combine lipid microbubbles with poly lactic-co-glycolic acid (PLGA) nanospheres and prepare a novel drug microbubble vector, and to explore the efficiency of covalent bonding and static adsorption in combining ultrasound microbubbles with active PLGA nanospheres.Technical imaging and therapy innovations: Preparation of a novel drug-loading ultrasound microbubble—early resultsHong-hong Wang, Hai-tao Ran, Zhi-gang Wang, Ya-ping Zhang, Lan Hao10.1016/j.clinimag.2011.10.011Clinical Imaging 36, 3 (2012)2012-01-20Clinical Imaging2012-01-20363S0899-7071(11)X0009-8Product Review216217http://www.clinicalimaging.org/article/PIIS0899707111001781/abstract?rss=yesAbstract: Developmental anomalies of the aortic arch vessels and persistent trigeminal artery that is the most common of the four anomalous carotid–basilar anastomoses are repeatedly reported in the literature as separate entities. Herein we report a previously undescribed variant including the coexistence of persistent trigeminal artery, truncus bicaroticus and direct origin of left vertebral artery from aortic arch.Aortic arch vessel anomalies associated with persistent trigeminal arteryMehrzad Lotfi, Seyed Ali Nabavizadeh, Amin Abolhasani Foroughi10.1016/j.clinimag.2011.08.018Clinical Imaging 36, 3 (2012)2011-10-13Clinical Imaging2011-10-13363S0899-7071(11)X0009-8Case Reports218220http://www.clinicalimaging.org/article/PIIS0899707111001793/abstract?rss=yesAbstract: Tracheal diverticulum is a paratracheal air cyst in connection with the trachea. It may be congenital or acquired. Congenital tracheal diverticula in infants are rare. Imaging techniques such as high-resolution computed tomography and three-dimensional reconstruction of the airway are useful for diagnosis. Here we report three cases with congenital tracheal diverticula, which were diagnosed by imaging techniques.Tracheal diverticula in infants: a report of three casesGuohong Zhu, Dan Xu, Hongzhen Xu, Shuxian Li, Meiping Lu, Zhimin Chen10.1016/j.clinimag.2011.08.019Clinical Imaging 36, 3 (2012)2011-10-13Clinical Imaging2011-10-13363S0899-7071(11)X0009-8Case Reports221223http://www.clinicalimaging.org/article/PIIS0899707111001896/abstract?rss=yesAbstract: A 76-year-old woman had 131I accumulation within the mediastinum in the setting of thyroid carcinoma remission. Extensive diagnostic imaging including computed tomography (CT), magnetic resonance imaging (MRI), endoscopic ultrasound, bronchoscopy, and subsequently a needle aspiration biopsy revealed that the mass was a bronchogenic cyst. Five-year clinical and laboratory follow-up showed that the patient was free from thyroid carcinoma recurrence.Radioiodine (131I) accumulation in bronchogenic cyst in the setting of thyroid carcinoma remissionUlku C. Turba, Onur Sildiroglu, Patrice K. Rehm10.1016/j.clinimag.2011.09.005Clinical Imaging 36, 3 (2012)2011-11-14Clinical Imaging2011-11-14363S0899-7071(11)X0009-8Case Reports224227http://www.clinicalimaging.org/article/PIIS0899707111001835/abstract?rss=yesAbstract: We present a rare case of incidentally found mobile thoracolithiasis in a 76-year-old cirrhotic patient on serial computed tomography scans performed before and after transarterial chemoembolization for hepatocellular carcinoma. Mobility and calcification are the important clue to diagnosing this benign condition and avoiding unnecessary surgery.Thoracolithiasis: a case reportSilanath Peungjesada, Pramod Gupta, Ann M. Mottershaw10.1016/j.clinimag.2011.08.023Clinical Imaging 36, 3 (2012)2011-11-02Clinical Imaging2011-11-02363S0899-7071(11)X0009-8Case Reports228230http://www.clinicalimaging.org/article/PIIS089970711100180X/abstract?rss=yesAbstract: We report the case of a 52-year-old female with multiple medical complaints and extensive prior clinical and imaging workup who presented to the emergency department with weakness and recurrent episodes of abdominal pain. She had had multiple inconclusive routine computed tomographic (CT) examinations. A 7-mm small bowel tumor was diagnosed on CT enterography and subsequently confirmed to be a carcinoid tumor of the ileum by enteroscopy and at surgery. The diagnosis was suggested prospectively utilizing CT enterography performed in the emergency radiology suite.Beyond routine abdominal CT in the ER: a patient with indeterminate recurrent abdominal pain benefits from CT enterographyJoseph L. Gatlin, Kathryn Brown, Shou-Jiang Tang, Sunit Sebastian10.1016/j.clinimag.2011.08.020Clinical Imaging 36, 3 (2012)2011-10-13Clinical Imaging2011-10-13363S0899-7071(11)X0009-8Case Reports231235http://www.clinicalimaging.org/article/PIIS089970711100177X/abstract?rss=yesAbstract: Our purpose is to report a rare complication of an inferior vena cava (IVC) filter with vertebral bone penetration, interval fracture, subsequent endovascular management and outcome. We report a case of an IVC filter embedded within the second lumbar vertebral body and in which one of the primary struts fractured, which presented as chronic low back pain. The filter was retrieved percutaneously approximately 2 years after placement. A fractured small strut remained within the vertebral bone; patient's pain resolved. Symptomatic filter in situ should be retrieved even when fractured.Inferior vena cava filter presenting as chronic low back painMustafa T. Kendirli, Onur Sildiroglu, Dorothy L. Cage, Ulku C. Turba10.1016/j.clinimag.2011.08.017Clinical Imaging 36, 3 (2012)2011-10-13Clinical Imaging2011-10-13363S0899-7071(11)X0009-8Case Reports236238http://www.clinicalimaging.org/article/PIIS0899707111001859/abstract?rss=yesAbstract: Primary malignant fibrous histiocytoma (MFH) is extremely rare, and MFH arising from a hydronephrotic kidney has not been reported. When MFH originates from a long-standing hydronephrotic kidney, the imaging findings can include nearly invisible renal parenchyma and atrophy of the ureter and renal artery, in addition to the findings attributable to the MFH, and the MFH with hydronephrosis may be confused with a cystic renal cell carcinoma.Malignant fibrous histiocytoma arising from a hydronephrotic kidney: a case report and review of the literatureKi Hwan Kim, Seung Hwa Lee, Sang Hoon Cha, Young Sik Kim, Deuk Jae Sung10.1016/j.clinimag.2011.09.001Clinical Imaging 36, 3 (2012)2011-11-14Clinical Imaging2011-11-14363S0899-7071(11)X0009-8Case Reports239242http://www.clinicalimaging.org/article/PIIS0899707111001860/abstract?rss=yesAbstract: A 71-year-old man was referred to our hospital because of intermittent urine stream and postmicturition dribbling. Magnetic resonance imaging (MRI) results suggested the mass to be a malignant mesenchymal tumor arising from the left lobe of the prostate, on the basis of the presence of a beak sign. Radical prostatectomy and partial rectal excision with subsequent colostomy were performed. Contrary to preoperative MRI, no prostate involvement was found on histologic examination. Histopathologic and immunohistochemical findings showed typical characteristics of solitary fibrous tumors. The patient's postoperative course was uneventful. He showed no signs of recurrence and metastasis at 2-year follow-up.Pelvic solitary fibrous tumor originally diagnosed as prostatic in originRyosuke Ando, Daichi Kobayashi, Taku Naiki, Noriyasu Kawai, Shoichi Sasaki, Kenjiro Kohri10.1016/j.clinimag.2011.09.002Clinical Imaging 36, 3 (2012)2011-11-02Clinical Imaging2011-11-02363S0899-7071(11)X0009-8Case Reports243245http://www.clinicalimaging.org/article/PIIS0899707112000915/abstract?rss=yesCase reportsAntonio F. Govoni10.1016/j.clinimag.2012.02.013Clinical Imaging 36, 3 (2012)2012-03-29Clinical Imaging2012-03-29363S0899-7071(11)X0009-8Case Reports246246http://www.clinicalimaging.org/article/PIIS0899707112000897/abstract?rss=yesThis book, based on the radiologic evaluation of 100 pediatric cases, is dedicated to the residents training in pediatric radiology. The cases are presented in the right page and illustrated by clear images, 1 to 5, accompanied by clear clinical information.Anne Geoffray10.1016/j.clinimag.2012.02.011Clinical Imaging 36, 3 (2012)2012-04-05Clinical Imaging2012-04-05363S0899-7071(11)X0009-8Book Reviews247247http://www.clinicalimaging.org/article/PIIS0899707112000873/abstract?rss=yesThe book Imaging Painful Spine Disorders presents the various pathological processes related to the anatomical vertebral-medullary segments, including also other pathologies involving different anatomical segments but having a common clinical finding, the symptom of a painful spine. The pathologies, which can be responsible for the single symptom of a painful spine, are often associated with other symptoms and findings that can direct the physician to reach the correct diagnosis. These secondary symptoms are very variable and can be produced, for example, by a pathological degeneration of the spine or by an aneurysm of the abdominal aorta.Maja Ukmar10.1016/j.clinimag.2012.02.009Clinical Imaging 36, 3 (2012)2012-03-29Clinical Imaging2012-03-29363S0899-7071(11)X0009-8Book Reviews247248http://www.clinicalimaging.org/article/PIIS0899707112000903/abstract?rss=yesTraditional radiology has been and is the methodology used most frequently by orthopedic surgeons who, through the years, have learned to interpret its findings. Magnetic resonance imaging (MRI) has further increased the possibilities of radiologic imaging and also is the new type of imaging the orthopedic surgeons have used to maintain evaluating and interpreting the images obtained, even before asking the opinion of the radiologist. The complexity of magnetic resonance (MR) images, however, compared with those obtained by the traditional radiology calls for an orthopedic surgeon who knows the more complex techniques, a knowledge acquired in the majority of cases only through direct communication with the radiologist. This book, written by orthopedic surgeons and radiologists, gives their colleagues an instrument by which they can obtain that information necessary for the correct performance, then evaluation and interpretation of the osteoarticular imaging obtained by MR.Aldo Morra10.1016/j.clinimag.2012.02.012Clinical Imaging 36, 3 (2012)2012-04-05Clinical Imaging2012-04-05363S0899-7071(11)X0009-8Book Reviews248248