Clinical Imaging
Volume 35, Issue 4 , Pages 288-293, July 2011

Magnetic resonance spectroscopic imaging of benign prostatic tissue: findings at 3.0 T compared to 1.5 T—initial experience☆

Received 11 May 2010; accepted 10 July 2010. published online 01 September 2010.

Abstract 

In a retrospective study of 71 voxels of benign peripheral zone tissue from 3 men who underwent endorectal magnetic resonance (MR) spectroscopic imaging of the prostate at both 1.5 and 3 T, 21 voxels that appeared more malignant at 3 T to either of two readers demonstrated significantly higher levels of choline and polyamines at 3 T compared to 1.5 T using a Wilcoxon ranked-sum test; awareness of this selective amplification of these metabolic signals at high field strength may help avoid overdiagnosis of prostate cancer.

Keywords: Cancer, Prostate, MR, MR spectroscopy, 3 T

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☆ ACW was supported by NIBIB T32 training grant 1 T32 EB001631.

PII: S0899-7071(10)00151-8

doi:10.1016/j.clinimag.2010.07.005

Clinical Imaging
Volume 35, Issue 4 , Pages 288-293, July 2011

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