Computed tomographic criteria for the discrimination of subcentimeter lung nodules in patients with soft-tissue sarcomas

Dudeck, Oliver; Zeile, M.; Andreou, D.; Schnapauff, D.; Pech, M.; Wieners, G.; Ricke, J.; Reichardt, P.; Tunn, P.-U.

doi:10.1016/j.clinimag.2010.06.005

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Volume 35, Issue 3 , Pages 174-179, May 2011

Computed tomographic criteria for the discrimination of subcentimeter lung nodules in patients with soft-tissue sarcomas

Oliver Dudeck
- Department of Radiology and Nuclear Medicine, Leipziger Strasse 44, 31920 Magdeburg Magdeburg, Germany
- Department of Radiology, Charité, Campus Buch, Lindenberger Weg 80, 13125 Berlin, Germany
- Corresponding author. Leipziger Strasse 44, 31920 Magdeburg Magdeburg, Germany. Tel.: +49 391 67 13030; fax: +49 391 67 13029.
M. Zeile
- Department of Radiology and Nuclear Medicine, Leipziger Strasse 44, 31920 Magdeburg Magdeburg, Germany
- Department of Radiology, HELIOS Clinic Buch, Schwanebecker Chaussee 50, 13125 Berlin, Germany
D. Andreou
- Department of Surgical Oncology, HELIOS Clinic Buch, Lindenberger Weg 80, 13125 Berlin, Germany
D. Schnapauff
- Department of Radiology, Charité, Campus Buch, Lindenberger Weg 80, 13125 Berlin, Germany
M. Pech
- Department of Radiology and Nuclear Medicine, Leipziger Strasse 44, 31920 Magdeburg Magdeburg, Germany
G. Wieners
- Department of Radiology and Nuclear Medicine, Leipziger Strasse 44, 31920 Magdeburg Magdeburg, Germany
J. Ricke
- Department of Radiology and Nuclear Medicine, Leipziger Strasse 44, 31920 Magdeburg Magdeburg, Germany
P. Reichardt
- Department of Oncology, HELIOS Clinic Buch, Lindenberger Weg 80, 13125 Berlin, Germany
P.-U. Tunn
- Department of Surgical Oncology, HELIOS Clinic Buch, Lindenberger Weg 80, 13125 Berlin, Germany

Received 17 April 2010; accepted 21 May 2010. published online 09 July 2010.

Abstract

The aim of this study was to identify criteria for nodule characterization on chest computed tomography in patients with soft tissue sarcomas. In 195 patients, a total of 194 benign and 117 malignant subcentimeter lung nodules were retrospectively analyzed according to lesion size, shape, margins, density, and localization. Benign lesions more frequently displayed complex shape and were of ground-glass density (P<.0001, respectively). In contrast, round shape and solid density were more frequently found in malignant lesions (P<.0001, respectively).

Keywords: Characterization, Computed tomography, Lung nodules, Soft tissue sarcomas, Subcentimeter