Solid-pseudopapillary neoplasm of the pancreas: spectrum of findings on multidetector CT

Kawamoto, Satomi; Scudiere, Jennifer; Hruban, Ralph H.; Wolfgang, Christopher L.; Cameron, John L.; Fishman, Elliot K.

doi:10.1016/j.clinimag.2009.11.007

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Volume 35, Issue 1 , Pages 21-28, January 2011

Solid-pseudopapillary neoplasm of the pancreas: spectrum of findings on multidetector CT

Satomi Kawamoto
- The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins Medical Institutions, 601 North Caroline Street, Baltimore, MD 21287, USA
- Corresponding author. Department of Radiology, Johns Hopkins Medical Institutions, 601 N. Caroline Street, Baltimore, MD 21287, USA. Tel.: +1 410 955 9446; fax: +1 410 614 0341.
Jennifer Scudiere
- Department of Pathology, The Johns Hopkins Medical Institutions, 601 North Caroline Street, Baltimore, MD 21287, USA
- The Sol Goldman Pancreatic Cancer Research Center and The Johns Hopkins Medical Institutions, 601 North Caroline Street, Baltimore, MD 21287, USA
Ralph H. Hruban
- Department of Pathology, The Johns Hopkins Medical Institutions, 601 North Caroline Street, Baltimore, MD 21287, USA
- The Sol Goldman Pancreatic Cancer Research Center and The Johns Hopkins Medical Institutions, 601 North Caroline Street, Baltimore, MD 21287, USA
Christopher L. Wolfgang
- Department of Surgery, The Johns Hopkins Medical Institutions, 601 North Caroline Street, Baltimore, MD 21287, USA
- The Sol Goldman Pancreatic Cancer Research Center and The Johns Hopkins Medical Institutions, 601 North Caroline Street, Baltimore, MD 21287, USA
John L. Cameron
- Department of Surgery, The Johns Hopkins Medical Institutions, 601 North Caroline Street, Baltimore, MD 21287, USA
- The Sol Goldman Pancreatic Cancer Research Center and The Johns Hopkins Medical Institutions, 601 North Caroline Street, Baltimore, MD 21287, USA
Elliot K. Fishman
- The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins Medical Institutions, 601 North Caroline Street, Baltimore, MD 21287, USA

Received 1 October 2009; accepted 10 November 2009. published online 15 January 2010.

Abstract

Solid-pseudopapillary neoplasms of the pancreas are uncommon and usually occur in young women. They are generally large, encapsulated masses with mixture of solid, cystic, and hemorrhagic components. Some cases have atypical features; for example, they can form a small predominantly solid mass and produce dilatation of the main pancreatic duct. In this article we discuss and illustrate the spectrum of the appearances of this distinctive neoplasm on multidetector CT.

Keywords: Solid-pseudopapillary neoplasm, Pancreas, Solid and papillary epithelial neoplasm, Multidetector CT, Differential diagnosis