Diffusion-weighted MRI evaluation of breast cancer extension

Long-Hua, Qiu; Qin, Xiao; Wen-Tao, Yang; Feng, Tang; Kun-Wei, Shen; Bin, Wu; Ya-Jia, Gu

doi:10.1016/j.clinimag.2009.09.002

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Volume 34, Issue 2 , Pages 89-96, March 2010

Diffusion-weighted MRI evaluation of breast cancer extension

Qiu Long-Hua
- Department of Radiology, The Affiliated Cancer Hospital of Fudan University, Shanghai 200032, China
Xiao Qin
- Department of Radiology, The Affiliated Cancer Hospital of Fudan University, Shanghai 200032, China
Yang Wen-Tao
- Department of Pathology, The Affiliated Cancer Hospital of Fudan University, Shanghai 200032, China
Tang Feng
- Department of Radiology, The Affiliated Cancer Hospital of Fudan University, Shanghai 200032, China
Shen Kun-Wei
- Department of Breast Surgery, The Affiliated Cancer Hospital of Fudan University, Shanghai 200032, China
Wu Bin
- Department of Radiology, The Affiliated Cancer Hospital of Fudan University, Shanghai 200032, China
Gu Ya-Jia
- Department of Radiology, The Affiliated Cancer Hospital of Fudan University, Shanghai 200032, China
- Corresponding author. Department of Radiology, the Affiliated Cancer Hospital of Fudan University, 270 DongAn Road, Shanghai 200032, China. Tel.: +86 21 64175590 6034; fax: +86 21 64433384.

Received 30 April 2009; accepted 6 May 2009. published online 26 October 2009.

Abstract

Aim

To investigate the feasibility of using diffusion-weighted MR imaging (DWI) to accurately measure breast cancer extension.

Materials and Methods

The extensions of 59 breast lesions were investigated on DW images and apparent diffusion coefficient (ADC) maps and compared to the pathological exams.

Results

Three groups were observed: accurate, overdiagnosis, and false negative. There were no significant differences seen in accurate or false-negative group when b was 500 and 1000 s/mm² when two lesions in the overdiagnosis group at both b values.