Detection of lymph nodes in pelvic malignancies with computed tomography and magnetic resonance imaging

Saokar, Anuradha; Islam, Tina; Jantsch, Marion; Saksena, Mansi A.; Hahn, Peter F.; Harisinghani, Mukesh G.

doi:10.1016/j.clinimag.2009.07.004

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Volume 34, Issue 5 , Pages 361-366, September 2010

Detection of lymph nodes in pelvic malignancies with computed tomography and magnetic resonance imaging

Anuradha Saokar
- Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
- Division of Abdominal Imaging and Intervention, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Tina Islam
- Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
- Division of Abdominal Imaging and Intervention, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
- Corresponding author. Division of Abdominal Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, USA. Tel.: +1 617 724 4266; fax: +1 617 726 4891.
Marion Jantsch
- Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
- Division of Abdominal Imaging and Intervention, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Mansi A. Saksena
- Division of Abdominal Imaging and Intervention, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Peter F. Hahn
- Division of Abdominal Imaging and Intervention, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Mukesh G. Harisinghani
- Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
- Division of Abdominal Imaging and Intervention, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA

Received 10 June 2009; accepted 20 July 2009. published online 15 October 2009.

Abstract

Thirty patients with prostate or bladder cancer underwent CT and MRI for nodal staging. CT detected 189 nodes, and MRI detected 271 nodes. This difference was statistically significant in the external iliac (CT/MRI=73/87 nodes), obturator (CT/MRI=48/75 nodes), and internal iliac (CT/MRI=24/46 nodes) nodal chains. Based on size, the number of nodes detected by CT and MRI were as follows: 1–5 mm, CT/MRI=91/166; 6–10 mm, CT/MRI=91/98; >10 mm, CT/MRI=7/7 nodes. MRI detected significantly more lymph nodes in the size range of 1–5 mm.

Keywords: Lymph node metastasis, Computed tomography, Magnetic resonance imaging, Lymphotropic nanoparticle-enhanced MRI