Clinical Imaging
Volume 34, Issue 3 , Pages 211-221 , May 2010

Real-time contrast-enhanced ultrasound imaging of focal liver lesions in fatty liver

  • Guang-Jian Liu

      Affiliations

    • Department of Medical Ultrasonics, Institute of Diagnostic and Interventional Ultrasound, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
    • ,
  • Wei Wang

      Affiliations

    • Department of Medical Ultrasonics, Institute of Diagnostic and Interventional Ultrasound, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
    • ,
  • Xiao-Yan Xie

      Affiliations

    • Department of Medical Ultrasonics, Institute of Diagnostic and Interventional Ultrasound, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
    • ,
  • Hui-Xiong Xu

      Affiliations

    • Department of Medical Ultrasonics, Institute of Diagnostic and Interventional Ultrasound, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
    • ,
  • Zuo-Feng Xu

      Affiliations

    • Department of Medical Ultrasonics, Institute of Diagnostic and Interventional Ultrasound, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
    • ,
  • Yan-Ling Zheng

      Affiliations

    • Department of Medical Ultrasonics, Institute of Diagnostic and Interventional Ultrasound, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
    • ,
  • Jin-Yu Liang

      Affiliations

    • Department of Medical Ultrasonics, Institute of Diagnostic and Interventional Ultrasound, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
    • ,
  • Fuminori Moriyasu

      Affiliations

    • Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan
    • ,
  • Ming-De Lu

      Affiliations

    • Department of Hepatobiliary Surgery, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
    • Corresponding Author InformationCorresponding author. Department of Hepatobiliary Surgery, The First Affiliated Hospital of Sun Yat-Sen University, 58 Zhongshan Road 2, Guangzhou 510080, People's Republic of China. Tel.: +86 20 87765183; fax: +86 20 87765183.

Received 20 March 2009 ,Accepted 10 May 2009.

References 

  1. Claudon M, Cosgrove D, Albrecht T, et al. Guidelines and good clinical practice recommendations for contrast enhanced ultrasound (CEUS)—update 2008. Ultraschall Med. 2008;29:28–44
  2. Quaia E, Caliada F, Bertolotto M, et al. Characterization of focal liver lesions with contrast-specific US modes and a sulfur hexafluoride-filled microbubble contrast agent: diagnostic performance and confidence. Radiology. 2004;232:420–430
  3. von Herbay A, Vogt C, Willers R, Häussinger D. Real-time imaging with the sonographic contrast agent SonoVue: differentiation between benign and malignant hepatic lesions. J Ultrasound Med. 2004;23:1557–1568
  4. Ding H, Wang WP, Huang BJ, et al. Imaging of focal liver lesions: low-mechanical-index real-time ultrasonography with SonoVue. J Ultrasound Med. 2005;24:285–297
  5. Xu HX, Liu GJ, Lu MD, et al. Characterization of small focal liver lesions using real-time contrast-enhanced sonography: diagnostic performance analysis in 200 patients. J Ultrasound Med. 2006;25:349–361
  6. Konno K, Ishida H, Sato M, et al. Liver tumors in fatty liver: difficulty in ultrasonographic interpretation. Abdom Imaging. 2001;26:487–491
  7. Jeffrey RB, Ralls PW. The liver. In:  Jeffrey RB,  Ralls PW editor. Sonography of the abdomen. New York: Raven Press; 1995;p. 71–170
  8. Fracanzani AL, Burdick L, Borzio M, et al. Contrast-enhanced Doppler ultrasonography in the diagnosis of hepatocellular carcinoma and premalignant lesions in patients with cirrhosis. Hepatology. 2001;34:1109–1112
  9. Kim SH, Lee JM, Lee JY, et al. Value of contrast-enhanced sonography for the characterization of focal hepatic lesions in patients with diffuse liver disease: receiver operating characteristic analysis. AJR Am J Roentgenol. 2005;184:1077–1084
  10. Bartolotta TV, Taibbi A, Galia M, et al. Characterization of hypoechoic focal hepatic lesions in patients with fatty liver: diagnostic performance and confidence of contrast-enhanced ultrasound. Eur Radiol. 2007;17:650–661
  11. Bartolotta TV, Midiri M, Galia M, et al. Characterization of benign hepatic tumors arising in fatty liver with SonoVue and pulse inversion US. Abdom Imaging. 2007;32:84–91
  12. Scatarige JC, Scott WW, Donovan PJ, Siegelman SS, Sanders RC. Fatty infiltration of the liver: ultrasonographic and computed tomographic correlation. J Ultrasound Med. 1984;3:9–14
  13. Jacobs JE, Birnbaum BA, Shapiro MA, et al. Diagnostic criteria for fatty infiltration of the liver on contrast-enhanced helical CT. AJR Am J Roentgenol. 1998;171:659–664
  14. Burns PN. Instrumentation for contrast echocardiography. Echocardiography. 2002;19:241–258
  15. Wilson SR, Kim TK, Jang HJ, Burns PN. Enhancement patterns of focal liver masses: discordance between contrast-enhanced sonography and contrast-enhanced CT and MRI. AJR Am J Roentgenol. 2007;189:W7–W12
  16. Lin LW, Yang JJ, Lin XY, et al. Effect of fatty liver background on contrast-enhanced ultrasonographic appearance of focal nodular hyperplasia. Hepatobiliary Pancreat Dis Int. 2007;6:610–615
  17. Bartolotta TV, Midiri M, Scialpi M, et al. Focal nodular hyperplasia in normal and fatty liver: a qualitative and quantitative evaluation with contrast-enhanced ultrasound. Eur Radiol. 2004;14:583–591
  18. Liu GJ, Lu MD, Xu HX, et al. Real-time contrast-enhanced ultrasound imaging of infected focal liver lesions. J Ultrasound Med. 2008;27:657–666
  19. Catalano O, Sandomenico F, Raso MM, Siani A. Low mechanical index contrast-enhanced sonographic findings of pyogenic hepatic abscess. AJR Am J Roentgenol. 2004;182:447–450
  20. Xu HX, Lu MD, Liu GJ, et al. Imaging of peripheral cholangiocarcinoma with low-mechanical index contrast-enhanced sonography and SonoVue: initial experience. J Ultrasound Med. 2006;25:23–33
  21. Sherlock S, Dooley J. Nutritional and metabolic liver diseases. In:  Sherlock S,  Dooley J editor. Diseases of the liver and biliary system. London: Blackwell Sciences; 1997;p. 427–454
  22. Veenhuizen JJ, Drackley JK, Richard MJ, et al. Metabolic changes in blood and liver during development and early treatment of experimental fatty liver and ketosis in cows. J Dairy Sci. 1991;74:4238–4253

PII: S0899-7071(09)00178-8

doi: 10.1016/j.clinimag.2009.07.003

Clinical Imaging
Volume 34, Issue 3 , Pages 211-221 , May 2010

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