Clinical Imaging
Volume 33, Issue 6 , Pages 447-453, November 2009

Perfusion study of liver lesions with superparamagnetic iron oxide: distinguishing hepatocellular carcinoma from focal nodular hyperplasia

Department of Radiology, Tokyo Medical University, Tokyo, Japan

Department of Internal Medicine, Tokyo Medical University, Tokyo, Japan

Received 10 November 2008; accepted 14 January 2009. published online 26 February 2009.

Abstract 

We performed a perfusion study with superparamagnetic iron oxide (SPIO) and evaluated the possibility of acquiring hemodynamic imaging in hypervascular hepatocellular nodules. Single-slice computed tomography during arteriography (SCTA) and an SPIO perfusion study were performed and compared. The findings of the direction of blood flow in the lesion and the findings corresponding to the corona enhancement on the SPIO perfusion study agreed well with the findings of SCTA. In conclusion, SPIO perfusion is useful in evaluating the hemodynamics of hypervascular hepatocellular nodules.

Keywords: Corona enhancement, Dynamic study, MRI, SPIO

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PII: S0899-7071(09)00016-3

doi:10.1016/j.clinimag.2009.01.008

Clinical Imaging
Volume 33, Issue 6 , Pages 447-453, November 2009

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